Week 1 showcased some exciting results in college football, setting the stage for a thrilling season ahead. Some teams opted for matchups against FCS opponents to build up excitement and expectations for the season.
Week 2 presents an opportunity for teams to confirm or alter those narratives as they face tougher competition. The lineup includes in-state rivalries, renewed rivalries, potential upsets, and a top-10 clash in The Big House.
Honorable Mention: BYU at SMU (Friday), No. 23 Georgia Tech at Syracuse, Baylor at No. 11 Utah, South Carolina at Kentucky, Michigan State at Maryland, No. 19 Kansas at Illinois, Oregon State at San Diego State.
(All point spreads come from BetMGM; click here for live odds. All kickoff times are Eastern and on Saturday unless otherwise noted.)
10. USF (1-0) at No. 4 Alabama (1-0), 7 p.m., ESPN
The matchup between USF and Alabama may have a big point spread, but a lot has changed for both teams since their last meeting. It will be interesting to see how quarterback Jalen Milroe and the Alabama team, led by Nick Saban, face off against USF, who have shown improvement under coach Alex Golesh.
Line: Alabama -30.5
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9. UTSA (1-0) at Texas State (1-0), 4 p.m., ESPNU
The I-35 Rivalry between UTSA and Texas State features two strong Group of 5 contenders. Both teams are looking to secure a spot in the G5 College Football Playoff with a win in this matchup.
Line: Texas State -1.5
8. No. 17 Kansas State (1-0) at Tulane (1-0), Noon, ESPN
Kansas State faces a tougher challenge against Tulane after a dominant win in Week 1. Tulane, led by redshirt freshman quarterback Darian Mensah, is looking to replicate their past success against the Wildcats.
Line: Kansas State -9.5
7. Appalachian State (1-0) at No. 25 Clemson (0-1), 8 p.m., ACC Network
Appalachian State aims to upset Clemson, who is looking to bounce back from a rough start to the season. The Mountaineers have a history of taking down top teams and will provide a tough test for the Tigers.
Line: Clemson -17.5
Oklahoma State faces an SEC opponent in a matchup that will test both teams. The game provides an opportunity to see how both teams perform and what to expect from them moving forward.
Line: Oklahoma State -7.5
5. Colorado (1-0) at Nebraska (1-0), 7:30 p.m., NBC
Colorado and Nebraska renew their rivalry in a game that will feature promising young talent on both sides. The matchup will showcase the skills of true freshman quarterback Dylan Raiola, who impressed in Nebraska’s first game.
Line: Nebraska -7.5
4. Boise State (1-0) at No. 7 Oregon (1-0), 10 p.m., Peacock
Oregon looks to bounce back from a close win in their last game. Boise State, on the other hand, had a high-scoring victory and will be looking to continue their success against a tough opponent like Oregon.
Line: Oregon -19.5
3. No. 14 Tennessee (1-0) vs. No. 24 NC State (1-0), 7:30 p.m., ABC
Tennessee and NC State face off in what promises to be an exciting matchup. Both teams showed promise in their first games and will be looking to build on that success in this game.
Line: Tennessee -7.5
2. Iowa State (1-0) at No. 21 Iowa (1-0), 3:30 p.m., CBS
The Cy-Hawk series continues with Iowa State taking on Iowa in a matchup between two teams with high aspirations. The game will likely be a close, hard-fought battle between the intrastate rivals.
Line: Iowa -3
1. No. 3 Texas (1-0) at No. 10 Michigan (1-0), Noon, Fox
Two powerhouse teams, Texas and Michigan, face off in a highly anticipated matchup. Both teams are coming off wins and will be looking to assert their dominance in this early-season test.
Line: Texas -7.5
(Photo of Donovan Edwards: Gregory Shamus / Getty Images)